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Rulide

Generic Rulide (Roxithromycin)

Rulide is a macrolide antibiotic used to treat infections of of upper respiratory tract.
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150mg
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Common use

Rulide is a semi-synthetic macrolide antibiotic used for the treatment of mild to moderate infections of upper respiratory tract infections (acute pharyngitis, tonsillitis, sinusitis) caused by susceptible pathogens. Rulide prevents bacteria from growing, by inhibiting their protein synthesis.



Dosage and directions

Rulide is taken once or twice daily, a daily dose is 300 mg for adults.Usual course of treatment is 7-10 days.



Precautions

In patients with hepatic failure half-life of Rulide in serum increases. If liver disorders are severe (hepatic cirrhosis with jaundice and/or ascites), the dose of the medications should be corrected.

Small amounts of Rulide are excreted in human breast milk so breast feeding or treatment of the mother should be stopped if required.



Contraindications

Hypersensitivity to Rulide or macrolide antibiotics, concomitant therapy with vasoconstrictive ergotamine type medications.



Possible side effect

Most common side effects are: nausea, vomiting, diarrhea, epigastric pain, flatulence, headache, dizziness, malaises, hives, rash, swelling of tongue and face, moniliasis (candidiasis)



Drug interaction

Rulide is able to increase plasma levels of theophylline when co-administered. It also may affect activity of warfarin and erythromycin.



Missed dose

If you missed a dose take it as soon as you remember. If it almost time of your next dose just skip it and return to your regular schedule. Never double dose this medication.



Overdose

In case of serious and persistent symptoms of allergy (hives, swelling of face and tongue, rash) consult your doctor about medical attention. In general Rulide is well tolerated.



Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment

Metformin

Other names used:

  • Glucophage®

Active Ingredients:

  • Metformin Hydrochloride

The commercial name of the medication may differ from the brand one. Generic Metformin manufactured by Mankind Pharma is available under commercial name Metname.

How does Metformin work and what pharmaceutical group does it belong to?

Metformin is an hypoglycemic drug that belongs to a group of biguanidines. It works by decreasing the concentration of glucose in the blood through inhibition of gluconeogeneisis in the liver, decreasing the absorption of glucose from the GI tract and the utilization of glucose in the tissues. If Insulin is absent in the blood then metformin does not exert any effects. The drug stabilizes and decreases body weight.

Which conditions are treated with Metformin?

The preparation is indicated in treatment of Diabetes mellitus type II. Especially in cases which are accompanied by obesity.

What should a patient know before using Metformin?

The Metformin should not be used in cases of:

  • Hypersensitivity to any components of the preparation
  • Hyperglycemic coma
  • Ketoacidosis
  • Chronic liver failure
  • Acute myocardial infraction
  • Respiratory disorder
  • Dehydration
  • Infectious disease of different origin
  • Surgery
  • Pregnancy
  • Lactation period
  • Low calorie diet

The preparation should be used with caution in:

  • Elderly patients older then 60 years
  • Patients performing difficult physical activity

Which adverse effects may manifest when using the medication?

The side effects of Metformin include:

  • Gastrointestinal tract: nausea, vomiting, metallic taste, decreased appetite, dyspepsiam meteorism, abdominal pain
  • Metabolism: lactic acidosis, avitaminosis B12
  • Haemopoietic organs: megablast anemia
  • Allergic reactions: skin rash

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Metformin?

The drug is affected by the following:

  • Ethanol
  • Anticoagulants
  • H2-histamine receptor blockers
  • MAO inhibitors
  • Other diabetes treatments
  • Antibiotics
  • ACE inhibitors
  • Increased cholesterol treatment
  • Oral contraceptives
  • Corticosteroids
  • Adrenomimetics
  • Thyroid gland hormones
  • Diuretics
  • NSAID's
  • Narcotic analgesics
  • Antivirals
  • Neuroleptics

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Metformin is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.