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Plan B

Plan B (Levonorgestrel)

Levonorgestrel is a hormone used to prevent pregnancy. It is taken just after the intercourse, if no contraceptive methods were used during it, or the used method was not reliable.
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1,5mg
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1,5mg
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Common use

Levonorgestrel is a hormone used as a contraception medication it is similar to progesterone and is its racemic isomer (norgestrel), which is twice more potent. The drug changes condition of cervical mucus and uterine lining and hampers movement of sperm cells to the uterus and attachment of a fertilized egg to the uterus. Levonorgestrel is administered to prevent pregnancy within 72 hours after the intercourse, if no contraceptive methods were used during it, or the used method was not reliable.



Dosage and direction

Take the medication orally. Take two tablets this way: the first tablet is taken as soon as possible after the intercourse (not later than within 72 hours); the second tablet should be taken in 12 hours (but not later than 16 hours) after the first tablet. If you had vomiting within three hours after intake of any tablet, take one more tablet. Levonorgestrel tablet of 0.75 mg may be taken on any day of your menses only if your previous period was normal. After emergency treatment with Levonorgestrel local barrier methods of contraception should be used (e.g. a condom).



Precautions

Recurrent use of Levonorgestrel during one menstrual cycle is not recommended due to possible disorders of the period. The medication does not substitute regular contraception medication and should be used only in case of emergency. Emergency medication sometimes fails to prevent pregnancy. This medication excretes to the breast milk. Take the pills after breastfeeding to decrease negative effects on your baby and avoid breastfeeding after the treatment. Inform your doctor if you have a bleeding or blood-clotting disorder, diabetes, a vaginal infection, a sexually transmitted disease, pelvic infection, heart disease, high blood pressure, or a heart valve disorder.



Contraindications

Do not take Levonorgestrel if you are pregnant because the medication does not end the pregnancy which has already occurred. The medication cannot be used in patients with abnormal vaginal bleeding, untreated or uncontrolled pelvic infection, serious pelvic infection following a pregnancy or abortion within the past 3 months, uterine fibroid tumors, history of pelvic inflammatory disease (PID), past or present breast cancer, liver disease or liver tumor, cervical or uterine cancer; a recent abnormal Pap smear, decreased immunity (leukemia, AIDS, IV drug abuse).



Side effects

The most frequent adverse reactions of Levonorgestrel include nausea, irregular pap smear bleeding, delay of menses for more than 7 days, dizziness, headache, a pain in the lower abdomen, nausea, vomiting, tension of the mammary glands, fatigue.



Drug interaction

Simultaneous use of the drugs, which induce liver enzymes accelerates metabolism of Levonorgestrel. These drugs may reduce the effectiveness of Levonorgestrel: barbiturates, including primidon, phenytoin and carbamazepine and drugs that contain St. John's wort (Hypericum perforatum), rifampicin, ritonavir, rifabutin, griseofulvin. Drugs that contain Levonorgestrel may increase toxicity of cyclosporine.



Missed dose

Missed dose is not supposed as this medication is taken when needed.



Overdose

Vomiting and bleeding are possible. Contact your doctor if you suspect overdose.



Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Metformin

Other names used:

  • Glucophage®

Active Ingredients:

  • Metformin Hydrochloride

The commercial name of the medication may differ from the brand one. Generic Metformin manufactured by Mankind Pharma is available under commercial name Metname.

How does Metformin work and what pharmaceutical group does it belong to?

Metformin is an hypoglycemic drug that belongs to a group of biguanidines. It works by decreasing the concentration of glucose in the blood through inhibition of gluconeogeneisis in the liver, decreasing the absorption of glucose from the GI tract and the utilization of glucose in the tissues. If Insulin is absent in the blood then metformin does not exert any effects. The drug stabilizes and decreases body weight.

Which conditions are treated with Metformin?

The preparation is indicated in treatment of Diabetes mellitus type II. Especially in cases which are accompanied by obesity.

What should a patient know before using Metformin?

The Metformin should not be used in cases of:

  • Hypersensitivity to any components of the preparation
  • Hyperglycemic coma
  • Ketoacidosis
  • Chronic liver failure
  • Acute myocardial infraction
  • Respiratory disorder
  • Dehydration
  • Infectious disease of different origin
  • Surgery
  • Pregnancy
  • Lactation period
  • Low calorie diet

The preparation should be used with caution in:

  • Elderly patients older then 60 years
  • Patients performing difficult physical activity

Which adverse effects may manifest when using the medication?

The side effects of Metformin include:

  • Gastrointestinal tract: nausea, vomiting, metallic taste, decreased appetite, dyspepsiam meteorism, abdominal pain
  • Metabolism: lactic acidosis, avitaminosis B12
  • Haemopoietic organs: megablast anemia
  • Allergic reactions: skin rash

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Metformin?

The drug is affected by the following:

  • Ethanol
  • Anticoagulants
  • H2-histamine receptor blockers
  • MAO inhibitors
  • Other diabetes treatments
  • Antibiotics
  • ACE inhibitors
  • Increased cholesterol treatment
  • Oral contraceptives
  • Corticosteroids
  • Adrenomimetics
  • Thyroid gland hormones
  • Diuretics
  • NSAID's
  • Narcotic analgesics
  • Antivirals
  • Neuroleptics

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient:

Metformin is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.